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Panax Notoginseng Triol Saponins (PNTS) are triterpene saponins extracted from Panax notoginseng (Araliaceae). The core components are ginsenosides Rg1, R1, and Rb1. Their chemical structure is based on protopanaxadiol as the aglycone, exhibiting significant lipid solubility and biological activity. Pharmacological studies show that PNTS protects the cardiovascular system by inhibiting platelet aggregation (IC50=23.7μM), promoting the release of nitric oxide (NO) in vascular endothelial cells, scavenging free radicals (DPPH scavenging rate of 82.3%), and regulating the NF-κB inflammatory pathway.
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