Traditional Chinese Medicine Extract Series
Sanqi polysaccharides are natural active ingredients extracted from the roots, stems, and leaves of Panax notoginseng (Araliaceae), mainly composed of arabinogalactans and other complex polysaccharides, with a highly branched structure.
Ginsenoside Rg1 is a core active ingredient of Panax ginseng, belonging to the protopanaxadiol-type triterpene saponins. Its chemical structure is based on a dammarane-type tetracyclic triterpene skeleton, modified by glycosylation to form unique pharmacological activity. Studies have shown that Rg1 has multi-target regulatory capabilities, including activating the Akt/GSK-3β pathway to protect neurons, promoting the release of vascular endothelial nitric oxide (NO) to improve microcirculation, and enhancing microglial phagocytosis through the AMPK signaling pathway. It has significant antioxidant activity, with a DPPH radical scavenging rate of 85%, and can improve superoxide dismutase (SOD) activity and reduce malondialdehyde (MDA) production.
Ginsenoside Rb1 is one of the core active components of Panax ginseng in the Araliaceae family. It belongs to the protopanaxadiol-type triterpene saponin, with a dammarane-type tetracyclic triterpene as its skeleton, forming unique pharmacological activity through glycosylation modification. Studies have shown that Rb1 has multi-target regulation capabilities, including inhibiting calcium channels (IC50=23.7μM), promoting the release of vascular endothelial nitric oxide (NO), activating the Akt/GSK-3β pathway to protect neurons, and scavenging free radicals through the regulation of the Nrf2/ARE pathway (DPPH scavenging rate up to 85%). It has significant antioxidant activity, can improve superoxide dismutase (SOD) activity, reduce malondialdehyde (MDA) production, and reduce infarct volume by 38.5% in a cerebral ischemia-reperfusion model.
Huangteng Su is a natural alkaloid extracted from the dried stems of *Fibraurea recisa* Pierre, a plant belonging to the Menispermaceae family. Its core component is palmatine, an isoquinoline compound. It possesses a wide range of pharmacological activities, including broad-spectrum antibacterial activity (inhibiting *Staphylococcus aureus*, *Escherichia coli*, *Candida albicans*, etc.), anti-inflammatory activity (reducing the release of pro-inflammatory factors by inhibiting the NF-κB inflammatory pathway), antiviral activity (effective against influenza viruses, herpes simplex viruses, etc.), antioxidant activity (scavenging free radicals and enhancing SOD activity), and immunomodulatory activity (enhancing the phagocytic function of leukocytes). Studies have shown that Huangteng Su also has anti-tumor potential, exerting its effects by inducing tumor cell apoptosis and inhibiting angiogenesis.
