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Mango extract

Mango extract

Mango extract is a natural active ingredient extracted from the fruit, leaves, peel, and kernel of the mango tree. Core components include mangiferin (a flavonoid glycoside), polyphenols (such as catechin and epicatechin), carotenoids, and vitamin C.

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Asiaticoside

Asiaticoside

Asiaticoside is the core active ingredient of Centella asiatica (Centella asiatica) in the Apiaceae family, mainly containing asiaticoside, madecassoside and other pentacyclic triterpene esters. It has a wide range of pharmacological effects, exerting its efficacy by promoting fibroblast proliferation (collagen synthesis increased by 41.7%), inhibiting inflammatory pathways (such as NF-κB), and scavenging free radicals (DPPH scavenging rate up to 85%). Modern extraction techniques such as flash extraction can significantly enhance its anti-tumor activity, inducing apoptosis of tumor cells by activating the Bax/Caspase-3 pathway, with an inhibition rate exceeding 50% in a lung cancer model.

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ecdyson

ecdyson

Ecdysone is a naturally occurring steroid compound widely found in insects, plants (such as water dropwort), and microorganisms. Its core structure is a dammarane-type tetracyclic triterpenoid skeleton, modified by glycosylation to form bioactive compounds. As a key regulator of insect growth and development, ecdysone activates the ecdysone receptor (EcR), initiating a cascade reaction that induces insect molting and metamorphosis.

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Total saponins of Panax notoginseng

Total saponins of Panax notoginseng

Panax Notoginseng Saponins (PNS) are natural active ingredients extracted from the roots and stems of Panax notoginseng, a plant in the Araliaceae family. They mainly contain more than ten triterpene saponins, including ginsenosides Rg1, Rb1, Rd, and notoginsenoside R1. Its core pharmacological effects include: improving microcirculation by inhibiting platelet aggregation and regulating vascular endothelial function; clearing free radicals and enhancing SOD activity to resist oxidative stress; and inhibiting the NF-κB inflammatory pathway to reduce the release of pro-inflammatory factors such as TNF-α. Studies have shown that PNS can also induce apoptosis by blocking the tumor cell cycle (such as the S phase), and significantly inhibit angiogenesis of the chick chorioallantoic membrane in angiogenesis models.

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Panax notoginseng leaf extract

Panax notoginseng leaf extract

Sanqi leaf extract is a natural active ingredient extracted from the stems and leaves of Panax notoginseng (Araliaceae). Its core components are total saponins of Sanqi leaf (mainly 20 (S)-protopanaxadiol saponins such as ginsenosides Rb3, Rb1, and Rc), as well as flavonoids (such as quercetin-3-O-rutinoside) and polysaccharides. It exhibits significant pharmacological activities, including sedation and tranquilization (by inhibiting the central nervous system to prolong sleep time and improve symptoms of neurasthenia, with a total effective rate of 88.8%), anti-myocardial ischemia (reducing myocardial cell damage and improving electrocardiogram changes), lipid-lowering (reducing serum total cholesterol and triglyceride levels), antioxidant (scavenging free radicals and enhancing SOD activity), and anti-tumor effects (inhibiting the proliferation of various cancer cell lines such as glioma and pancreatic cancer).

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Tribulus saponin

Tribulus saponin

Panax Notoginseng Triol Saponins (PNTS) are triterpene saponins extracted from Panax notoginseng (Araliaceae). The core components are ginsenosides Rg1, R1, and Rb1. Their chemical structure is based on protopanaxadiol as the aglycone, exhibiting significant lipid solubility and biological activity. Pharmacological studies show that PNTS protects the cardiovascular system by inhibiting platelet aggregation (IC50=23.7μM), promoting the release of nitric oxide (NO) in vascular endothelial cells, scavenging free radicals (DPPH scavenging rate of 82.3%), and regulating the NF-κB inflammatory pathway.

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Sanqi polysaccharide

Sanqi polysaccharide

Sanqi polysaccharides are natural active ingredients extracted from the roots, stems, and leaves of Panax notoginseng (Araliaceae), mainly composed of arabinogalactans and other complex polysaccharides, with a highly branched structure.

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Ginsenoside Rg1

Ginsenoside Rg1

Ginsenoside Rg1 is a core active ingredient of Panax ginseng, belonging to the protopanaxadiol-type triterpene saponins. Its chemical structure is based on a dammarane-type tetracyclic triterpene skeleton, modified by glycosylation to form unique pharmacological activity. Studies have shown that Rg1 has multi-target regulatory capabilities, including activating the Akt/GSK-3β pathway to protect neurons, promoting the release of vascular endothelial nitric oxide (NO) to improve microcirculation, and enhancing microglial phagocytosis through the AMPK signaling pathway. It has significant antioxidant activity, with a DPPH radical scavenging rate of 85%, and can improve superoxide dismutase (SOD) activity and reduce malondialdehyde (MDA) production.

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Ginsenoside Rb1

Ginsenoside Rb1

Ginsenoside Rb1 is one of the core active components of Panax ginseng in the Araliaceae family. It belongs to the protopanaxadiol-type triterpene saponin, with a dammarane-type tetracyclic triterpene as its skeleton, forming unique pharmacological activity through glycosylation modification. Studies have shown that Rb1 has multi-target regulation capabilities, including inhibiting calcium channels (IC50=23.7μM), promoting the release of vascular endothelial nitric oxide (NO), activating the Akt/GSK-3β pathway to protect neurons, and scavenging free radicals through the regulation of the Nrf2/ARE pathway (DPPH scavenging rate up to 85%). It has significant antioxidant activity, can improve superoxide dismutase (SOD) activity, reduce malondialdehyde (MDA) production, and reduce infarct volume by 38.5% in a cerebral ischemia-reperfusion model.

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Huangteng Su

Huangteng Su

Huangteng Su is a natural alkaloid extracted from the dried stems of *Fibraurea recisa* Pierre, a plant belonging to the Menispermaceae family. Its core component is palmatine, an isoquinoline compound. It possesses a wide range of pharmacological activities, including broad-spectrum antibacterial activity (inhibiting *Staphylococcus aureus*, *Escherichia coli*, *Candida albicans*, etc.), anti-inflammatory activity (reducing the release of pro-inflammatory factors by inhibiting the NF-κB inflammatory pathway), antiviral activity (effective against influenza viruses, herpes simplex viruses, etc.), antioxidant activity (scavenging free radicals and enhancing SOD activity), and immunomodulatory activity (enhancing the phagocytic function of leukocytes). Studies have shown that Huangteng Su also has anti-tumor potential, exerting its effects by inducing tumor cell apoptosis and inhibiting angiogenesis.

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